师资队伍
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个人简介 | |||||||||||||||||||||||||
汪泉,博士,ylzzcom永利总站线路检测教授,博士生导师,国家级重大人才工程A类青年项目入选者。2002年至2012年在北京大学学习,获北京大学理学博士学位,后在美国范德堡大学从事生物信息学研究工作十余年。目前研究方向为人类复杂疾病的生物信息处理与分析,基于多组学数据融合构建统计模型,解释复杂疾病的遗传学机理,发掘有重定向潜力的药物。在Nature Neuroscience, Molecular Psychiatry, Genome Biology, Bioinformatics等期刊发表论文27篇,引用超1500次,H index为16,研究成果引起新华网、福克斯新闻等知名大众媒体的广泛关注。受邀担任Briefings in Bioinformatics, Human Genetics, Bioinformatics等多个国际学术期刊审稿人。 | |||||||||||||||||||||||||
学术成果(1=共同第一作者) | |||||||||||||||||||||||||
1.Fang J1, Zhang P1, Wang Q1, Chiang CW, Zhou Y, Hou Y, Xu J, Chen R, Zhang B, Lewis SJ, Leverenz JB, Pieper AA, Li B, Li L, Cummings J, Cheng F. Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease. Alzheimer's research & therapy, 14(1):1-23, 2022 2.Yang H, Chen R, Wang Q, Wei Q, Ji Y, Zhong X, Li B. TVAR: assessing tissue-specific functional effects of non-coding variants with deep learning. Bioinformatics, 38(20):4697-4704, 2022 3.Wang Q1, Chen R1, Cheng F, Wei Q, Ji Y, Yang H, Zhong X, Tao R, Wen Z, Sutcliffe JS, Liu C, Cook EH, Cox NJ, Li B. A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data. Nature Neuroscience, 22(5):691-699, 2019 4.Patton SM, Wang Q, Hulgan T, Connor JR, Jia P, Zhao Z, Letendre SL, Ellis RJ, Bush WS, Samuels DC, Franklin DR, Kaur H, Iudicello J, Grant I, Kallianpur AR. Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults. Fluids and Barriers of the CNS, 14(1):11, 2017 5.Wang Q, Yu H, Zhao Z, Jia P. EW_dmGWAS: edge-weighted dense module search for genome-wide association studies and gene expression profiles. Bioinformatics, 31(15):2591-2594, 2015 6.Wang Q, Jia P, Cheng F, Zhao Z. Heterogeneous DNA methylation contributes to tumorigenesis through inducing the loss of co-expression connectivity in colorectal cancer. Genes, Chromosomes and Cancer, 54(2):110-121, 2015 7.Zhao Z, Xu J, Chen J, Kim S, Reimers M, Bacanu SA, Yu H, Liu C, Sun J, Wang Q, Jia P, Xu F, Zhang Y, Kendler KS, Peng Z, Chen X (2014). Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder. Molecular Psychiatry, 20(5):563-572, 2015 8.Jia P, Wang Q, Chen Q, Hutchinson K, Pao W, Zhao Z. MSEA: detection and quantification of mutation hotspots through mutation set enrichment analysis. Genome Biology, 15(10):489, 2014 9.Wang Q, Peng P, Qian M, Wan L, Deng M. Hybridization and amplification rate correction for Affymetrix SNP arrays. BMC medical genomics, 5(24), 2012. 10.Wang Q, Wan L, Li D, Zhu L, Qian M, Deng M. Searching for bidirectional promoters in Arabidopsis thaliana. BMC Bioinformatics, 10(Suppl 1):S29, 2009. | |||||||||||||||||||||||||